PENGARUH TERAPI OKSIGEN HIPERBARIK TERHADAP KADAR TESTOSTERON PADA TIKUS MODEL SINDROMA OVARIUM POLIKISTIK DENGAN RESISTENSI INSULIN
DOI:
https://doi.org/10.30649/obj.v3i1.25Keywords:
hyperbaric oxygen therapy, level of testosteron, ovarium syndrome, polycystics, insulin resistanceAbstract
Background:Polycystic ovary syndrome (PCOS) is an endocrine disorder that
has the broadest and best in women often springs reproduktif age. Factors
underlying the recovery of PCOS are excessive androgens, insulin resistance, and
disturbance of gonadotropin dynamics. Excessive androgen causes LH and FSH
to develop. In the theory hyperbaric oxygen therapy allows to increase sensitivity
tissue to insulin. The . The purpose of this research was to know effect using
hyperbaric oxygen therapy 2.4 ATA 3x30 minutes for 5 sessions on testosterone
levels on rats model of Polycystic Ovary Syndrome with insulin resistance.
Metode:The research is experimental with post test only control group design.
The total sample used as 12 rats that is divided into 2 groups. Independent
variable is therapeutic oxygen hiperbarik, dependent variable testosteron level
from blood sample of rats and control variables are room temperature and
standard feed and control variables of androgen injection, types and specifications
of experimental animals, cage size and animal care. Data analysis of this study
was processed using Mann Whitney U test.
Result:The results of using Mann Whitney U Test with p-value = 0,150 > α
(0.05), showed no difference between testosterone levels in the experimental
group given androgen injection with the group of animals given androgen
injection and hyperbaric oxygen therapy.
Conclusion:Therapy oxygen hyperbarik has not been effecting testosteron levels
in white rats (Rattus Norvegicus) model syndroma ovarium polycystic with
resistensi insulin
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