@article{Sandy_Liliawanti_Kurnia_2018, title={PENGARUH PEMBERIAN EKSTRAK RUMPUT LAUT COKELAT (Sargassum duplicatum) TERHADAP PENINGKATAN KADAR HEMOGLOBIN PADA DARAH TIKUS JANTAN (Rattus norvegicus) GALUR WISTAR ANEMIA YANG DI INDUKSI NANO2}, volume={4}, url={https://ocean-biomedicina.hangtuah.ac.id/index.php/journal/article/view/57}, DOI={10.30649/obj.v4i1.51}, abstractNote={<p>Background: In Indonesia, the prevalence of iron deficiency anemia reaches 25,2 percent, it indicates <br>that anemia is a medical condition in society that needs attention. Brown seaweed (Sargassum <br>duplicatum) is a group of algae that contains minerals such as iron and vitamin B12. So that the <br>content in Sargassum duplicatum can be used for anemia therapy that serves as the main forming <br>hemoglobin. <br>Objective: The purpose of this experimental research was to determine the administration of <br>Sargassum duplicatum affects the increase in blood haemoglobin levels of rats that are anemia <br>induced NaNO2..<br>Methods: This research used the Post-test only control group design, the samples were 30 male rats <br>divided into 3 treatment groups (K0, K1, and K2). The process of treating anemia in rats using sodium <br>nitrite (NaNO2) at a dose of 125 mg / KgBB. K0 group is a group that is not treated. K1 group is a group <br>that was given NaNO2 for 18 days without dieting Sargassum duplicatum. The K2 group was the group <br>that was given NaNO2 for 18 days and received the Sargassum duplicatum diet at a dose of 2.45 <br>g/kgBB for 14 days.<br>Result: From this research it can be seen that K0 has an average hemoglobin level of 12,71 g/dL, K1 has <br>an average hemoglobin level of 11.96 g / dL, and K2 has an average hemoglobin level of 12,99 g/dL <br>which shows that descriptively there is a difference between groups K1 and K2. Based on the KruskalWallis statistical test, a value of 0,290 was obtained so that p &gt; 0.05 showed that H0 was accepted, <br>which means there was no difference in the administration of Sargassum duplicatum in increasing <br>blood hemoglobin levels in anemic rats.<br>Conclusion: From the results of this research, the conclusion in descriptively there was an increase in <br>the blood hemoglobin level of white rats in the group receiving Sargassum duplicatum extract therapy <br>but it was not statistically significant.</p>}, number={1}, journal={Oceana Biomedicina Journal}, author={Sandy, Emy Noviana and Liliawanti, Liliawanti and Kurnia, Wachjudi}, year={2018}, month={Jan.}, pages={1–10} }