Dental Calculus as The Unique Calcified Oral Ecosystem A Review Article

Natallia Pranata


The prevalence of periodontal disease in Indonesians is very high, which is around 95%, and 70% of these values occur above 30 years or the adult age group. There is controversy about whether dental calculus is an etiological factor in periodontal disease, or is it just a predisposing factor. Dental Calculus is a calcified oral ecosystem or dental plaque, can accumulate on supragingival or subgingival. Plaque is a bacterial biofilm complex on the tooth surface, including pathogenic microorganisms that invade periodontal tissue. Periodontal disease is the result of interactions between pathogens and the host immune system. Damage to periodontal tissue can occur if the pathogenicity of the microflora is more dominant in the immune response. In calcified conditions, these microorganisms lose their pathogenicity. The dental calculus is one form of the body's defense mechanism against pathogens. But the accumulation of dental calculus, with its rough surface, is a predisposing factor for plaque accumulation. The oral ecosystem trapping on the unique calcified material which are called dental calculus.

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Carranza FA, Klokkevold PR, Newman MG, et al. Carranza’s Clinical periodontology. 12th ed. St. Louis, Missouri: Elsevier, Saunder, 2015.

Notohartojo IT, Sihombing M. Faktor resiko pada penyakit jaringan periodontal gigi di Indonesia. Bul Penelit Sist Kesehat 2015; 18: 87–94.

Notohartojo IT, Lely Suratri MA. Menyikat gigi, monsumsi buah dan sayur, aktivitas fisik, diabetes mellitus dengan jaringan periodontal gigi di Indonesia, tahun 2013. Bul Penelit Sist Kesehat 2016; 19: 219–225.

Warinner C, Speller C, Collins MJ. A new era in palaeomicrobiology: prospects for ancient dental calculus as a long-term record of the human oral microbiome. Philos Trans R Soc B Biol Sci 2014; 370: 1–11.

Metcalf JL, Ursell LK, Knight R. Ancient human oral plaque preserves a wealth of biological data. Nat Genet 2014; 46: 321–323.

Dumitrescu AL. Etiology and pathogenesis of periodontal disease. 1st ed. Heidelberg: Springer, 2010.

Nanci A. Ten cate’s oral histology: development, structure, and function. 8th ed. Quebec, Canada: Elsevier, Mosby, 2012.

Kweon HH-I, Lee J-H, Youk T, et al. Panoramic radiography can be an effective diagnostic tool adjunctive to oral examinations in the national health checkup program. J Periodontal Implant Sci 2018; 48: 317–325.

Brundin M, Figdor D, Sundqvist G, et al. DNA binding to hydroxyapatite: A potential mechanism for preservation of microbial DNA. J Endod 2013; 39: 211–216.

Yaprak E, Yolcubal I, Sinanoğlu A, et al. High levels of heavy metal accumulation in dental calculus of smokers: a pilot inductively coupled plasma mass spectrometry study. J Periodontal Res 2017; 52: 83–88.

Fialová D, Skoupý R, Drozdová E, et al. The application of scanning electron microscopy with energy-dispersive x-ray spectroscopy (SEM-EDX) in ancient dental calculus for the reconstruction of human habits. Microsc Microanal Off J Microsc Soc Am Microbeam Anal Soc Microsc Soc Can 2017; 23: 1207–1213.

Jersie-Christensen RR, Lanigan LT, Lyon D, et al. Quantitative metaproteomics of medieval dental calculus reveals individual oral health status. Nat Commun 2018; 9: 1–11.

Buckley S, Usai D, Jakob T, et al. Dental calculus reveals unique insights into food items, cooking and plant processing in prehistoric Central Sudan. PLoS ONE 2014; 9: 1–10.

Weyrich LS, Dobney K, Cooper A. Ancient DNA analysis of dental calculus. J Hum Evol 2015; 79: 119–124.



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Published by: Universitas Hang Tuah, Surabaya, Jawa Timur, Indonesia

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